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alkyne-containing fragment

" in MedChemExpress (MCE) Product Catalog:

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Click Chemistry

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-151782
    H-(Gly)3-Lys(N3)-OH

    		ADC Linker Others
    The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. Polyglycine fragments containing up to 7 glycines are reported to bind to surfaces and have potential application in nanotechnology constructs: constructs of Gly7-NHCH2-fragment containing peptides bind on mica surface in aqueous solution .
    H-(Gly)3-Lys(N3)-OH
  • HY-151746
    N3-Gly-Gly-Gly-OH

    		ADC Linker Others
    N3-Gly-Gly-Gly-OH is a oligo-Gly click chemistry reagent containing an azide group. Oligo-Gly also has been used as linker to combine different subunits of dimeric or oligomeric proteins or to create artificial multi-domain proteins. By modification into Gly-Gly-Gly-Ser motifs high solubility can be achieved . N3-Gly-Gly-Gly-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    N3-Gly-Gly-Gly-OH

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